Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations

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What is the Generic Name for Sinemet?

carbidopa/levodopa

What is the Trade Name for carbidopa/levodopa?

Sinemet

What are the Indications of Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations?

Parkinson’s disease

What are the Actions of Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations?

levodopa is converted to dopamine and works as a neurotransmitter, carbidopa prevents the
destruction of levodopa allowing it to cross the blood brain barrier

What is the Therapeutic Class of Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations?

Antiparkinson agent

What is the Pharmacologic Class of Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations?

Dopamine Agonist

What are the Nursing Considerations of Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations?

may cause orthostatic hypotension
may cause dark urine
weeks to months to take effect
do not use with MAOIs
do not use with glaucoma, melanoma
assess for parkinsonian symptoms
instruct patient to take as directed

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