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Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations

What is the Generic Name for Sinemet?

carbidopa/levodopa

What is the Trade Name for carbidopa/levodopa?

Sinemet

What are the Indications of Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations?

Parkinson’s disease

What are the Actions of Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations?

levodopa is converted to dopamine and works as a neurotransmitter, carbidopa prevents the
destruction of levodopa allowing it to cross the blood brain barrier

What is the Therapeutic Class of Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations?

Antiparkinson agent

What is the Pharmacologic Class of Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations?

Dopamine Agonist

What are the Nursing Considerations of Carbidopa/levodopa (Sinemet) Nursing Pharmacology Considerations?

  • may cause orthostatic hypotension
  • may cause dark urine
  • weeks to months to take effect
  • do not use with MAOIs
  • do not use with glaucoma, melanoma
  • assess for parkinsonian symptoms
  • instruct patient to take as directed

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