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Chlorpromazine (Thorazine) Nursing Pharmacology Considerations

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What is the Generic Name for Thorazine?

chlorpromazine

What is the Trade Name for chlorpromazine?

Thorazine

What are the Indications of Chlorpromazine (Thorazine) Nursing Pharmacology Considerations?

second line treatment of schizophrenia and psychosis, nausea/vomiting, pre-op sedation, acute
intermittent porphyria, headache, bipolar

What are the Actions of Chlorpromazine (Thorazine) Nursing Pharmacology Considerations?

exhibits anticholinergic activity, alters effects of dopamine in CNS

What is the Therapeutic Class of Chlorpromazine (Thorazine) Nursing Pharmacology Considerations?

Antipsychotic, antiemetic

What is the Pharmacologic Class of Chlorpromazine (Thorazine) Nursing Pharmacology Considerations?

phenothiazines (dopamine D2 receptor antagonist)

What are the Nursing Considerations of Chlorpromazine (Thorazine) Nursing Pharmacology Considerations?

may cause neuroliptic malignant syndrome, sedation, tardive dyskineisa, hypotenstion,
agranulocytosis
assess mental status prior to and during treatment
monitor blood pressure
ensure patient is taking medication
monitor CBC and liver function tests
instruct patient not to skip doses or double dose.

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