Platelets (PLT) play a role in coagulation, hemostasis, and thrombus formation. Platelets are the smallest blood cell, damaged vessels send out signals that result in platelets traveling to the area and becoming “active”.
What is the Normal Range for Platelets?
100,000 – 450,000 cells/mcL
What are the Indications for Platelets?
Determine clotting vs bleeding disorders
What would cause Increased Levels of Platelets?
Malignancy
Polycythemia Vera
Postsplenectomy syndrome
Rheumatoid Arthritis (RA)
Iron-deficiency anemia
Hemolytic anemia
Tuberculosis
Birth control
What would cause Decreased Levels of Platelets?
Idiopathic Thrombocytopenia (ITP)
Inherited thrombocytopenia disorders:
Wiskott-Aldrich Syndrome
Bernard-Soulier Syndrome
Zieve Syndrome
Infection:
Hepatitis
Human Immunodeficiency Virus (HIV)
Measles
Sepsis
Hypersplenism
Hemorrhage
Leukemia
Lymphoma
Drug Therapy:
Aspirin
Ibuprofen
Sulfa antibiotics
Hydralazine
Thiazide diuretics
Systemic Lupus Erythematosus (SLE)
Hemolytic anemia’s
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