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Trimethoprim/sulfamethoxazole (Bactrim/TMP-SMZ)

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What is the Generic Name for Bactrim/TMP-SMZ?

Trimethoprim/sulfamethoxazole

What is the Trade Name for Trimethoprim/sulfamethoxazole?

Bactrim/TMP-SMZ

What are the Indications of Trimethoprim/sulfamethoxazole (Bactrim/TMP-SMZ)?

  • Bronchitis
  • UTI
  • Diarrhea
  • Pneumonia
  • Multiple types of infection

What are the Actions of Trimethoprim/sulfamethoxazole (Bactrim/TMP-SMZ)?

Bacteriacidal by preventing metabolism of folic acid

What is the Therapeutic Class of Trimethoprim/sulfamethoxazole (Bactrim/TMP-SMZ)?

Anti-infectives, antiprotozoals

What is the Pharmacologic Class of Trimethoprim/sulfamethoxazole (Bactrim/TMP-SMZ)?

Folate antagonists, sulfonamides

What are the Nursing Considerations of Trimethoprim/sulfamethoxazole (Bactrim/TMP-SMZ)?

  • May cause renal damage, Steven Johnsons Syndrome – rash, pseudomembranous colitis, nausea, vomiting, diarrhea, rash, agranulocytosis, aplastic anemia, phlebitis
  • Contraindicated with sulfa allergies
  • Monitor CBC
  • Obtain cultures prior to initiating therapy
  • Monitor intake and output
  • Instruct patient to complete dose
  • Drink 8-10 glasses of water

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