06.02 Clopidogrel (Plavix)

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Included In This Lesson

Outline

Generic Name

Clopidogrel

Trade Name

Plavix

Indication

Atherosclerotic events, MI, CVA, PVD, acute coronary syndrome

Action

Inhibits platelet aggregation

Therapeutic Class

Antiplatelet agent

Pharmacologic Class

Platelet aggregation inhibitors

Nursing Considerations

• May cause GI bleeding, neutropenia, hypercholesterolemia
• May increase risk for bleeding in warfarin, aspirin, heparin
• Can increase risk for bleeding with garlic, ginkgo, ginger
• Monitor for signs of bleeding
• Monitor bleeding times
• Monitor CBC and platelet count
• Discontinue use 5-7 days before surgery