06.09 Alteplase (tPA, Activase)
MI, acute ischemic stroke, occluded central lines
Converts plasminogen to plasmin which degrades the fibrin found in clots
• Contraindicated in active bleeding
• Monitor closely for signs of bleeding (petechiae)
○ q 15 min X1hr o q 15-30 min X 8 hr
• Use caution with patient who have had recent surgery
• May cause intracranial hemorrhage
• Monitor for anaphylaxis
• Use caution with uncontrolled hypertension
• Assess neuro status during therapy
Cornell Note-Taking System Instructions:
- Record: During the lecture, use the note-taking column to record the lecture using telegraphic sentences.
- Questions: As soon after class as possible, formulate questions based onthe notes in the right-hand column. Writing questions helps to clarifymeanings, reveal relationships, establish continuity, and strengthenmemory. Also, the writing of questions sets up a perfect stage for exam-studying later.
- Recite: Cover the note-taking column with a sheet of paper. Then, looking at the questions or cue-words in the question and cue column only, say aloud, in your own words, the answers to the questions, facts, or ideas indicated by the cue-words.
- Reflect: Reflect on the material by asking yourself questions, for example: “What’s the significance of these facts? What principle are they based on? How can I apply them? How do they fit in with what I already know? What’s beyond them?
- Review: Spend at least ten minutes every week reviewing all your previous notes. If you do, you’ll retain a great deal for current use, as well as, for the exam.
For more information, visit www.nursing.com/cornell