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08.02 Bupropion (Wellbutrin)

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Name

Bupropion

Trade Name

Wellbutrin

Indication

Depression, smoking cessation, treat ADHD in adults

Action

Not well understood, ↑ dopaminergic and noradrenergic transmission via reuptake

Therapeutic Class

Antidepressants, smoking deterrents

Pharmacologic Class

Aminoketones

Nursing Considerations

• May lead to seizures, suicidal thoughts
• Do not administer if patient is taking MAOI
• Use caution with renal and liver impairment
• Assess mental status
• Instruct patient to avoid alcohol (may lead to hallucinations, seizures,
anxiety)

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