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11.07 Captopril (Capoten)

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Generic Name

Captopril

Trade Name

Capoten

Indication

Hypertension, management of CHF, decrease progression of DM neuropathy

Action

Block conversion of angiotensin I to angiotensin II, increases renin levels and
decreases aldosterone leading to vasodilation

Therapeutic Class

Antihypertensives

Pharmacologic Class

ACE Inhibitor

Nursing Considerations

• Can cause neutropenia – check WBCs regularly
• Use cautiously with potassium supplements and potassium sparing diuretics
• Use cautiously with diuretic therapy
• Administer 1 hour before meals
• Monitor blood pressure often
• Monitor weight and fluid status
• Monitor renal profile
• Monitor CBC frequently
• May lead to Rhabdomyolysis
• Dry cough

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Module 0 – Pharmacology Course Introduction

Module 3 – Disease Specific Medications

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