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12.10 Acyclovir (Zovirax)

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Generic Name

Acyclovir

Trade Name

Zovirax

Indication

Genital herpes, herpes zoster, chicken pox

Action

Interferes with viral DNA synthesis

Therapeutic Class

Antiviral

Pharmacologic Class

Purine analogues

Nursing Considerations

• May cause seizures, renal failure, Stevens-Johnson syndrome, thrombotic
thrombocytopenic purpura syndrome, diarrhea, dizziness, nausea
• Monitor renal panel during administration
• Assess lesions
• Instruct patient to use proper protection during sexual intercourse

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