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12.14 Ciprofloxacin (Cipro)

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Generic Name

Ciprofloxacin

Trade Name

Cipro

Indication

Urinary tract infections, gonorrhea, respiratory tract infections, bronchitis,
pneumonia, skin and bone infections, infectious diarrhea, abdominal infections

Action

Inhibits bacterial DNA synthesis

Therapeutic Class

Anti-infectives

Pharmacologic Class

Fluoroquinolone

Nursing Considerations

• Contraindicated in allergies
• May cause QT prolongation, avoid use with other drugs that can cause QT
prolongation
• Can cause seizures, arrhythmias, pseudomembranous colitis, anaphylaxis,
Stevens Johnson syndrome
• May decrease effects of phenytoin
• Monitor renal panel
• Assess for infection, obtain cultures prior to therapy
• Monitor liver function tests

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