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12.28 Cephalexin (Keflex)

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Generic Name

Cephalexin

Trade Name

Keflex

Indication

Skin infections, pneumonia, UTI, otitis media

Action

Bactericidal: binds to bacterial cell wall leading to cell death

Therapeutic Class

Anti-infectives

Pharmacologic Class

Cephalosporin 1st generation

Nursing Considerations

• Contraindicated with cephalosporin and serious penicillin allergies.
• May need lead to seizures, pseudomembranous colitis, diarrhea, phlebitis
at IV site, anaphylaxis
• Assess infection and allergies
• Obtain cultures prior to therapy
• Monitor bowel function
• May lead to superinfection
• May cause elevated liver enzymes

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