17.02 Bismuth Subsalicylate (Pepto-Bismol)

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Generic Name

Bismuth subsalicylate

Trade Name

Kaopectate, Pepto-Bismol


Diarrhea, heartburn, indigestion, H. pylori associated ulcer


Stimulates the absorption of fluids and electrolytes in the intestinal wall, reduction in hypermotility of the stomach, and binds to toxins.

Therapeutic Class

Antidiarrheal, antiulcer, antacid

Pharmacologic Class


Nursing Considerations

• Contraindicated in aspirin hypersensitivity
• Increase risk for impaction with geriatric and pediatric patients
• Monitor liver profile
• Bismuth may interfere with radiologic exams