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20.03 Magnesium Sulfate

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Generic Name

magnesium sulfate

Trade Name

MgSO4

Indication

treatment of hypomagnesaemia, hypertension, preterm labor, torsade de pointes, asthma, anticonvulsant with eclampsia

Action

magnesium plays a role in muscle excitability

Therapeutic Class

mineral and electrolyte replacements/supplements

Pharmacologic Class

minerals/electrolytes

Nursing Considerations

  • use caution with renal insufficiency
  • may cause decreased respiratory rate, arrythmias, hypotension, muscle weakness
  • monitor EKG and respiratory status
  • monitor Mg levels
  • ensure dosage with secondary practitioner
  • Calcium gluconate is the antidote
    • Magnesium toxicity results in respiratory depress and loss of deep tendon reflexes

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