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22.04 ASA (Aspirin)

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Generic Name

Acetylsalicylic Acid

Trade Name

Bayer Aspirin

Indication

Rheumatoid arthritis, osteoarthritis, ischemic stroke and MI prophylaxis Action

Action

Inhibits the production of prostaglandins which leads to a reduction of fever and inflammation, decreases platelet aggregation leading to a decrease in ischemic diseases

Therapeutic Class

Antipyretics, non-opioid analgesics

Pharmacologic Class

Salicylates

Nursing Considerations

• Use caution in bleeding disorders, chronic alcohol use
• May lead to Stevens-Johnson syndrome, laryngeal edema, and anaphylaxis
• Increases risk for bleeding with warfarin, heparin, and clopidogrel
• Increased risk for GI bleeding with NSAID use
• Monitor liver function tests
• Concurrent use with alcohol may increase risk for GI bleeding
• Aspirin with viral infections can cause Reye’s syndrome

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