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22.05 Celecoxib (Celebrex)

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Generic Name

Celecoxib

Trade Name

Celebrex

Indication

Osteoarthritis, rheumatoid arthritis, acute pain

Action

Decreases pain and inflammation by inhibiting synthesis of prostaglandins

Therapeutic Class

Antirheumatics/NSAID

Pharmacologic Class

Cox 2 inhibitor

Nursing Considerations

• Use caution with cardiovascular disease
• Increases risk for MI, CVA, thrombosis
• May cause GI bleeding, Stevens-Johnson syndrome, dermatitis
• Notify provider for new-onset abdominal pain or black stool

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