Nalbuphine (Nubain) Nursing Considerations

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Generic Name


Trade Name



pain, analgesia during labor, sedation before surgery, supplement to balance anesthesia


alters perception and response to pain, causes CNS depression

Therapeutic Class

Opioid Analgesic

Pharmacologic Class

opioid agonists/analgesics

Nursing Considerations

• use caution with head trauma
• can cause dizziness, headache, nausea, vomiting, respiratory depression
• do not use with MAOIs
• assess pain
• may cause respiratory depression in newborn
• asses hemodynamic parameters
• may elevate pancreatic enzymes
• Narcan (naloxone) is the antidote

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Hey guys, let’s talk about NEN also known as new vein. This is an injectable medication. So the therapeutic class or how the drug works in the body is an opioid analgesic in the pharmacologic class or the chemical effect of Ning is an opioid agonist. So Ning works by altering the perception of the response to pain by causing CNS depression. We use now bine for pain, for analgesia, during labor, for sedation before surgery, and also as a supplement to anesthesia. Some of the side effects that we see with N bine are dizziness, headache, nausea, and vomiting. 

So let’s take a look at some of the nursing considerations for NEN use caution in patients who have head trauma, because it can elevate ICP. NEN may cause respiratory depression in adults and in newborns. And it may elevate pancreatic enzymes in the event of receiving too much of this medication, Narcan or Naloxone is the antidote and do not use in patients who are also on Mao eyes, assess your patient’s hemodynamic parameters and also their pain response while on now be bine. So Navine is highly dependent on the liver. So if your patient has liver issues, it is critical that a lower dose is started and then the patient is monitored even closely than you would sum ’em without liver issues. That’s it for Nin or new vein now go out and be your best self today. And as always happy nursing.

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