Olanzapine (Zyprexa) Nursing Considerations

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Generic Name


Trade Name



schizophrenia, mania, depression, anorexia nervosa, nausea/vomiting related to chemotherapy


antagonizes dopamine and serotonin

Therapeutic Class

antipsychotic, mood stabilizers

Pharmacologic Class


Nursing Considerations

• do not use while breastfeeding
• can cause neurolyptic malignant syndrome, seizures, suicidal thoughts, insomnia, tardive
dyskinesia, agranulocytosis, constipation, tremors
• assess mental status
• monitor hemodynamics
• assess blood sugars
• assess intake and output
• monitor liver function tests

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Hey guys, let’s talk about alanine, also known as Zyprexa. This is an oral medication, as you can see here with the tablets, and it also comes as an injection, the therapeutic class of Lanine or how it works in the body is an antipsychotic and also a mood stabilizer. The pharmacologic class, or the chemical effect of Lanine is a D benzodiazepine. So Lanine works by antagonizing dopamine in serotonin, which is why we use this drug for the management of schizophrenia, mania, depression, anorexia nervosa, and a also nausea and vomiting related to chemotherapy with Lanine. We can see side effects, including insomn suicidal thoughts, constipation, and also tremors. 

Let’s take a look at a few nursing considerations for alanine. Be sure to assess your patient’s mental status. Remember what this drug is used for. Also assess their blood sugar and intake an output while on alanine, your patient’s hemodynamics and liver function tests should be monitored. And alanine may cause in serious situations. Neuroleptic malignant syndrome, tardive dyskinesia seizures and a granulocyte hosts. It is important to know and teach that if your patient is breastfeeding, they should definitely not be taking this medication. So there is a black box warning for injectable Lanine patients receiving this medication injected should E in a healthcare facility only, and they should be observed for three hours following because alanine can cause post-injection delirium and sedation syndromes. That’s it for Lanine or Zyprexa. Now go out and be your best self today. And as always happy nursing.

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