Sertraline (Zoloft) Nursing Considerations

Join to watch the full lesson now.

Included In This Lesson

Study Tools


Generic Name


Trade Name



major depressive disorder, OCD, anxiety


inhibits uptake of serotonin allowing for higher quantities available within synaptic cleft

Therapeutic Class


Pharmacologic Class


Nursing Considerations

• do not use with MAOIs
• can cause neurolyptic malignant syndrome, suicidal thoughts, drowsiness, insomnia, diarrhea,
dry mouth, tremors, serotonin syndrome, sexual dysfunction
• monitor mood changes in patient
• takes 1-4 weeks for therapy to be effective.

Join to watch the full lesson now.


Okay, let’s take a look at the drug. Citraline also known as Zoloft. This is an oral medication. As you can see here, the therapeutic class, or how Citraline works in the body is an anti while the pharmacologic class or its chemical effect is an SS R I or serotonin selective reuptake inhibitor Erline works by inhibiting the uptake of serotonin, which remember this is sometimes known as the half chemical making higher quantities available within the synaptic cleft. So we use this drug for the treatment of major depressive disorder for O C D or obsessive compulsive disorder, and also for anxiety. 

So some of the side effects that we see with Citraline or SSRIs in general are dry mouth tremors, drowsiness, and diarrhea, some nursing considerations for Citraline. This drug may cause neuroleptic malignant syndrome, suicidal thoughts, serotonin syndrome, and also sexual dysfunction. Be sure to monitor any mood changes in your patients. It’s important to teach the patient that this drug takes one to four weeks for therapy to be effective. And this is super important. Guys do not use Seline with Mao. So guys compared to other SSRIs Citraline has the fewest drug interactions. However, it does have the highest rate of diarrhea and male sexual dysfunction within this drug class and guys, most of the time, the side effects are way more important to the, than any drug interactions, and really can be a reason why they decide to stop taking this medication. That’s it for Citraline or Zoloft now go out and be your best self today and as always happy nursing.

Join to watch the full lesson now.