Streptokinase (Streptase) Nursing Considerations

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Generic Name


Trade Name



pulmonary embolism, DVT, occluded lines, arterial thrombus


converts plasminogen to plasmin which degrades fibrin clots

Therapeutic Class


Pharmacologic Class

plasminogen activators

Nursing Considerations

• contraindicated with active bleeding, hypersensitivity, bronchospasm, intracranial hemorrhage,
• begin therapy as soon as possible
• monitor vital signs continuously
• monitor closely for bleeding
• monitor hemodynamics
• avoid invasive procedures

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Okay, let’s talk about the drug. Streptokinase also known as Strase. This is an injectable medication, and here you can see streptokinase in its structural form, the therapeutic class of streptokinase or how it works in the body is a thrombolytic and the pharmacologic class, or the chemical effect of streptokinase is a plasma Mengen activator streptokinase works by converting plasma Mengen to plasma, which degrades vibrant clots we use streptokinase for the treatment of pulmonary embolism, D V T line occlusion and arterial thrombo thrombus. Some of the side effects that we see with streptokinase are blurred vision, dizziness, confusion, and fever, a few nursing considerations for streptokinase monitor your patient’s pH Vitaly signs continuously during administration of streptokinase monitor very closely for any bleeding and monitor all of their hemodynamics avoid invasive procedures. While on streptokinase streptokinase is contraindicated in patients who are actively bleeding, have a hypersensitivity to streptokinase have bronchospasms intracranial hemorrhage or severe hypotension streptokinase should be started. Immediately teach the patient to report any surgical procedures, active, bleeding, or history of stroke. Guys, in patients who receive streptokinase following an MI, they should actually also receive aspirin immediately following streptokinase that’s it for strepto kin or strep taste. Now go out and be your best self today, and as always happy nursing.

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