Trimethoprim-Sulfamethoxazole (Bactrim) Nursing Considerations

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Generic Name


Trade Name



bronchitis, UTI, diarrhea, pneumonia, multiple types of infection


bacteriacidal by preventing metabolism of folic acid

Therapeutic Class

anti-infectives, antiprotozoals

Pharmacologic Class

folate antagonists, sulfonamides

Nursing Considerations

• may cause renal damage, Steven Johnsons Syndrome – rash, pseudomembranous colitis, nausea,
vomiting, diarrhea, rash, agranulocytosis, aplastic anemia, phlebitis
• contraindicated with sulfa allergies
• monitor CBC
• obtain cultures prior to initiating therapy
• monitor intake and output
• instruct patient to complete dose
• drink 8-10 glasses of water

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Hey guys, this one is a mouthful. Let’s talk about trimethoprim sulfur methodol also known as TRO. This is an oral medication at, as you can see here, and it also comes in an IV form. The therapeutic class of trimethoprim sulfamethoxazole is an anti-infective agent and also an an protozoal agent, the pharmacologic class or its chem chemical effect in the body is a folate antagonist, a as well as a sulfide trimethoprim Ulfa meth meth all is a Tal agent preventing the metabolism of folic acid. We use this medication for bronchitis, for UTIs diarrhea, pneumonia, and for multiple types of infections. 

Some other side effects that we see with Bactrum can cause things like rash, nausea, vomiting, and diarrhea, a few nursing considerations for trimethoprim sulfamethoxazole or Bactrum monitor your patients intake and output as well as their seed C obtain cultures prior to the SAR of therapy, if they are needed. This drug is contraindicated in patients who have a sulfur allergy, and it may cause renal damage Stevens Johnson syndrome, a Grani low cytosis aplastic anemia, flub, and pseudo me colitis, make sure the patient knows that they have to complete the entire dose, even if they’re feeling better. And also they should drink eight to 10 glasses of water a day while on this medication. So guys with BA there is a risk of sudden death with pain patients taking BA with an ARB or ACE inhibitor. The mechanism is not very clear, but on patients who are on an anti-hypertensive medication, like an ARB or ACE inhibitor, it may be in the best interest to hold this hypertensive medication. If they absolutely need to be on Bru and use the shortest course of this, anti-infective possible, that’s it for tri Metre Ulfa meth ol or Bru now go out and be your best self today. And as always happy nursing.

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