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28.02 Epinephrine (EpiPen)

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Generic Name

Epinephrine

Trade Name

Adrenalin, EpiPen

Indication

Asthma and COPD exacerbations, allergic reactions, cardiac arrest, anesthesia adjunct

Action

Affects both beta1 and beta2 also has alpha agonist properties resulting in bron-
chodilation and increases in HR and BP. Inhibits hypersensitivity reactions.

Therapeutic Class

Antiasthmatic, bronchodilator, vasopressor

Pharmacologic Class

Adrenergic agonist

Nursing Considerations

• Side effects include: angina, tachycardia, hypertension, restlessness,
nervousness, hyperglycemia
• Use with MAOI may lead to hypertensive crisis
• Patients should not use stimulants (caffeine, guarana, etc)
• Excessive use may cause bronchospasm
• Assess lung sounds, pulse, BP, and other hemodynamic parameters
• Monitor for chest pain
• Instruct patient to use as directed
• Patient should insure adequate fluid intake to liquefy secretions
• Mouth should be rinsed after inhalation
• Beta blockers may negate effects
• May increase blood glucose levels

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  • Question 1 of 2

A nurse is caring for a client admitted for NSTEMI who suddenly goes unresponsive. The nurse notes no pulse, calls a code blue, and begins compressions. The provider arrives and orders a dose of epinephrine. What is the appropriate concentration and dose for this situation?

  • Question 2 of 2

A nurse is administering Epinephrine during a cardiac arrest. The nurse knows that Epinephrine produces its effects by stimulating which receptors? Select all that apply.

Module 0 – Pharmacology Course Introduction
Module 3 – Disease Specific Medications

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