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28.02 Epinephrine (EpiPen)

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Generic Name


Trade Name

Adrenalin, EpiPen


Asthma and COPD exacerbations, allergic reactions, cardiac arrest, anesthesia adjunct


Affects both beta1 and beta2 also has alpha agonist properties resulting in bron-
chodilation and increases in HR and BP. Inhibits hypersensitivity reactions.

Therapeutic Class

Antiasthmatic, bronchodilator, vasopressor

Pharmacologic Class

Adrenergic agonist

Nursing Considerations

• Side effects include: angina, tachycardia, hypertension, restlessness,
nervousness, hyperglycemia
• Use with MAOI may lead to hypertensive crisis
• Patients should not use stimulants (caffeine, guarana, etc)
• Excessive use may cause bronchospasm
• Assess lung sounds, pulse, BP, and other hemodynamic parameters
• Monitor for chest pain
• Instruct patient to use as directed
• Patient should insure adequate fluid intake to liquefy secretions
• Mouth should be rinsed after inhalation
• Beta blockers may negate effects
• May increase blood glucose levels