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22.08 Ketorolac (Toradol)

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Generic Name

ketorolac

Trade Name

Toradol

Indication

pain

Action

pain relief due to prostaglandin inhibition by blocking of the enzyme cyclooxygenase (COX)

Therapeutic Class

nonsteroidal anti-inflammatory agents, nonopioid analgesics

Pharmacologic Class

pyrroziline carboxylic acid

Nursing Considerations

• may cause GI bleeding, Stevens-Johnson Syndrome, anaphylaxis, drowsiness
• should not exceed 5 days of therapy
• bleeding risk increased with garlic, ginger, and ginkgo
• may decrease effectiveness of hypertensive medications and diuretics

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