Osmolality Lab Values

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What is the Lab Name for Osmolality Lab Values?


What is Osmolality in terms of Nursing Labs?

Osmolality is a measure of the particles in solution. The size, shape, and charge of the particles do not impact the osmolality

What is the Normal Range for Osmolality?

261 – 280 mOsm/kg

What are the Indications for Osmolality?

  • Monitor:
    • Electrolyte balance
    • Acid-Base balance
    • Hydration
  • Evaluate function of antidiuretic hormone.

What would cause Increased Levels of Osmolality?

  • Dehydration
  • Azotemia
  • Hypercalcemia
  • Hyperosmolar Hyperglycemia Syndrome (HHS)
  • Hypernatremia
  • Diabetes Insipidus
  • Hyperglycemia
  • Mannitol therapy
  • Uremia
  • Severe pyelonephritis
  • Shock
  • Ketosis

What would cause Decreased Levels of Osmolality?

  • Hyponatremia
  • Syndrome of Inappropriate Antidiuretic Hormone (SIADH)
  • Overhydration

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