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12.15 Levofloxacin (Levaquin)

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Generic Name

levofloxacin

Trade Name

Levaquin

Indication

urinary tract infections, gonorrhea, respiratory tract infections, bronchitis, pneumonia, skin and bone
infections

Action

inhibits DNA synthesis in bacteria

Therapeutic Class

Anti-infective

Pharmacologic Class

fluoroquinolone

Nursing Considerations

• contraindicated in allergies
• may cause QT prolongation, avoid use with other drugs that can cause QT prolongation
• can cause seizures, arrythmias, pseudomembranous colitis, anaphylaxis, Stevens Johnson
syndrome
• may decreased of phenytoin
• monitor renal panel
• assess for infection, obtain cultures prior to therapy
• monitor liver function tests

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