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09.03 Metformin (Glucophage)

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Generic Name

metformin

Trade Name

Glucophage

Indication

management of Type II DM, PCOS

Action

decreases glucose production in the liver, decreases absorption, increases cellular insulin sensitivity

Therapeutic Class

Antidiabetic

Pharmacologic Class

Biguanide

Nursing Considerations

• do not use with renal dysfunction, metabolic acidosis
• may cause diarrhea, nausea, vomiting, lactic acidosis
• monitor patient closely for ketoacidosis and lactic acidosis, discontinue medication immediately
if acidotic
• may cause metallic taste
• instruct patient that medication does not cure diabetes

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