APREPITANT (Aprepitant) Nursing Considerations

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What is the Generic Name

APREPITANT

What is the Trade Name for APREPITANT

Aprepitant

What is the Indication for APREPITANT

  • 1 INDICATIONS AND USAGE Aprepitant is a substance P/neurokinin 1 (NK 1 ) receptor antagonist. Aprepitant capsules are indicated ‚Ä¢ in combination with other antiemetic agents, in patients 12 years of age and older for prevention of: ‚Ä¢ acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy (HEC) including high-dose cisplatin ( 1.1 ) ‚Ä¢ nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy (MEC) ( 1.1 ) ‚Ä¢ for prevention of postoperative nausea and vomiting (PONV) in adults ( 1.2 ) Limitations of Use : ( 1.3 ) ‚Ä¢ Aprepitant has not been studied for treatment of established nausea and vomiting. ‚Ä¢ Chronic continuous administration of aprepitant is not recommended. 1.1 Prevention of Chemotherapy Induced Nausea and Vomiting (CINV) Aprepitant capsules, in combination with other antiemetic agents, are indicated in patients 12 years of age and older for the prevention of: ‚Ä¢ acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy (HEC) including high-dose cisplatin. ‚Ä¢ nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy (MEC). 1.2 Prevention of Postoperative Nausea and Vomiting (PONV) Aprepitant capsules are indicated in adults for the prevention of postoperative nausea and vomiting. 1.3 Limitations of Use ‚Ä¢ Aprepitant has not been studied for the treatment of established nausea and vomiting. ‚Ä¢ Chronic continuous administration of aprepitant is not recommended because it has not been studied, and because the drug interaction profile may change during chronic continuous use.

 

 

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References: https://open.fda.gov/

 

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