13.05 Quetiapine (Seroquel)

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Included In This Lesson

Outline

Generic Name

quetiapine

Trade Name

Seroquel

Indication

schizophrenia, depressive disorder, mania

Action

dopamine and serotonin antagonist

Therapeutic Class

antipsychotic, mood stabilizers

Pharmacologic Class

none

Nursing Considerations

• may cause neurolyptic malignant syndrome, seizures, dizziness, palpitations, weight gain,
anorexia
• QT interval prolongation
• don’t use with CNS depressants
• assess weight frequently
• monitor liver function test and CBC
• may increase cholesterol