Included In This Lesson
Study Tools
Outline
Generic Name
mannitol
Trade Name
Osmitrol
Indication
increased ICP, oliguric renal failure, edema, increased intraocular pressure
Action
inhibits reabsorption of water and electrolytes by increasing osmotic pressure, excreted by kidneys
Therapeutic Class
diuretic
Pharmacologic Class
osmotic diuretic
Nursing Considerations
• may cause phlebitis at IV site
• may cause dehydration, fluid and electrolyte imbalances
• monitor neuro status
• administer via a filter
Transcript
Hey guys, let’s talk about, manitol also known as OSL. This is an injectable medication, as you can see here. So remember the therapeutic class of a drug is how the drug works in the body and for manitol, this is a diuretic. The pharmacologic class is the chemical effect of the drug, which is an osmotic diuretic. So manitol works by inhibiting reabsorption of water and electrolytes in the nephron by decreasing osmotic pressure excreted by the kidneys we use manitol for increased intracranial pressure for oligo renal failure for edema and for intraocular pressure. So some of the side effects we see with manitol are dehydration through its action as a diuretic fluid and electrolyte balance in is for that same reason and also phlebitis at the IV site.
So with manitol neuro status should be assessed and monitored. Also manitol may cause anaphylaxis. So teach the signs of hypersensitivity or anaphylaxis to your, and also when administering manitol know that it must be administered by a filter and concentrations that are greater than 20%. So guys, it is super important to visually inspect manitol before giving it to your patient because crystallization can, can occur in the bottle. And I have personally seen this on more than one occasion. So yes, it does happen also guys, if ex extra occurs, it can cause skin necrosis. So keep that in mind when administering to your patient, that’s it for manitol or O out I’ll go out and be your best self today. And as always happy nursing, all.
Tarang Patel, DNP-NA, RN, CCRN, RPh 
Nichole Weaver, MSN/Ed, RN, CCRN 
Miriam Wahrman, MSN/Ed, RNC-MNN 
Kara Tarr, BSN, RN 
Nacole Riccaboni, MSN, AGACNP-BC, FNP-BC, CCRN, CMC 