Alkaline Phosphatase Lab Values

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Outline

What is the Lab Name for Alkaline Phosphatase Lab Values?

Alkaline Phosphatase

What is Alkaline Phosphatase in terms of Nursing Labs?

Alkaline phosphatase (ALP) is located in several places in the body: liver, intestines, biliary tract, bones, placenta. Different isoenzymes of ALP can be used to determine different disorders: liver, bone, intestine, certain cancers. It can also be used to determine bone turnover in postmenopausal women.

What is the Normal Range for Alkaline Phosphatase?

40-130 U/L

What are the Indications for Alkaline Phosphatase?

    • Hepatobiliary disease
    • Malignancies
    • Bone disease
    • Bone damage in renal patients

What would cause Increased Levels of Alkaline Phosphatase?

  • Liver disease
  • Bone disease
  • Pregnancy
  • Amyloidosis
  • Lung cancer
  • Pancreatic cancer
  • Congestive heart failure
  • Ulcerative colitis
  • Hodgkin’s disease
  • Chronic renal failure
  • Sarcoidosis

What would cause Decreased Levels of Alkaline Phosphatase?

  • Hypophophatasia
  • Anemia
  • Kwashiorkor
  • Cretinism
  • Hypothyroidism
  • Zinc or magnesium deficiency
  • Scurvy

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