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Cholinergic Crisis – Signs and Symptoms Nursing Mnemonic

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SLUDGE

  • S-Salivation
  • L-Lacrimation
  • U-Urination
  • D-Defecation
  • G-Gastric upset
  • E-Emesis

Description

A cholinergic crisis can occur if the body stops properly breaking down Acetylcholine. This can cause overactivity of Acetylcholine at the neuromuscular junction. Acetylcholine is part of Rest & Digest (Parasympathetic) – so we see overactive digestion and secretion.

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