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So let's take a look at a few nursing considerations for diphenhydramine. Be sure to assess the purpose of giving this medication prior to administering. Also assess your patient's allergies, sleep patterns, cough, and lung sounds during therapy. Remember that there are some anticholinergic effects that occur with diphenhydramine, including constipation, dry mouth, blurred, vision, and sedation. Some additional issues can occur, including chest tightness, thick secretions, and hypotension. An extra little bit of information: be especially careful if your patient has dementia and is on any acetylcholinesterase inhibitors; diphenhydramine in these medications directly inhibit each other, meaning this could lead to worsening dementia and worsening of the issue the patient was on was taking diphenhydramine for in the first place. And also guys teach the patient to avoid over-the-counter cough and cold remedies. That's it for diphenhydramine or Benadryl. Now go out and be your best self today and as always happy nursing.
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