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Morphine works by binding to opiate receptors in the central nervous system, which alters the perception of pain, producing general depression of the CNS. Morphine is used for pain. It's used for pulmonary edema and also for the treatment of myocardial infarctions. Remember morphine causes depression of the CNS. So with this, we can see things like hypotension. Opioids in general can cause GI issues like constipation, nausea, and vomiting. Let's take a look at some of the nursing considerations for morphine. In addition to the side effects already mentioned, morphine can cause alterations in mentation. So before and during the administration of morphine assess the patient's blood pressure, pulse, and respiratory rates. You must use caution in patients who are also on MAOIs in the event of an overdose. The antidote for opioids is Narcan or Naloxone. Teach the patient to use as directed and also to report signs of a reaction, including hives, difficulty breathing, or facial swelling. Guys, morphine can cause histamine dumping from mast cells. It's not really known why, but because of this, the patient can get phlebitis or also a rash, but this isn't actually an allergy and the patient can still receive morphine. So be aware of this with morphine and recognize it if you need to. That's it for morphine or MS Contin. Now go out and be your best self today. And as always happy nursing.
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