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Outline
What is the generic name?
CEFOTETAN AND DEXTROSE
What is the Trade Name for CEFOTETAN AND DEXTROSE?
Cefotetan and Dextrose
What are the Indications for CEFOTETAN AND DEXTROSE?
- 1 INDICATIONS AND USAGE Cefotetan for Injection and Dextrose Injection is a cephalosporin antibacterial indicated for the treatment of the following infections caused by susceptible isolates of the designated bacteria ( 1 ): Urinary tract infections ( 1.1 ); Lower respiratory tract infections ( 1.2 ); Skin and skin structure infections ( 1.3 ); Gynecologic infections ( 1.4 ); Intra-abdominal infections ( 1.5 ); Bone and joint infections ( 1.6 ); Prophylaxis ( 1.7 ); To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefotetan for Injection and Dextrose Injection and other antibacterial drugs, Cefotetan for Injection and Dextrose Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. ( 1.8 ) 1.1 Urinary Tract Infections Cefotetan for Injection and Dextrose Injection is indicated for the treatment of urinary tract infections caused by E. coli , Klebsiella spp (including K. pneumoniae ), Proteus mirabilis , Proteus vulgaris , Providencia rettgeri , and Morganella morganii . 1.2 Lower Respiratory Tract Infections Cefotetan for Injection and Dextrose Injection is indicated for the treatment of lower respiratory tract Infections caused by Streptococcus pneumoniae , Staphylococcus aureus (methicillin susceptible), Haemophilus influenzae , Klebsiella species (including K. pneumoniae ), E. coli , Proteus mirabilis , and Serratia marcescens . 1.3 Skin and Skin Structure Infections Cefotetan for Injection and Dextrose Injection is indicated for the treatment of skin and skin structure infections due to Staphylococcus aureus (methicillin susceptible), Staphylococcus epidermidis (methicillin susceptible), Streptococcus pyogenes , Streptococcus species, Escherichia coli , Klebsiella pneumoniae , Peptococcus niger , Peptostreptococcus species. 1.4 Gynecologic Infections Cefotetan for Injection and Dextrose Injection is indicated for the treatment of gynecologic Infections caused by Staphylococcus aureus (methicillin susceptible), Staphylococcus epidermidis (methicillin susceptible), Streptococcus species, Streptococcus agalactiae , E. coli , Proteus mirabilis , Neisseria gonorrhoeae , Bacteroides fragilis , Prevotella melaninogenica, Bacteroides vulgatus , Fusobacterium species, and gram-positive anaerobic cocci (including Peptococcus niger and Peptostreptococcus species). Cefotetan has no activity against Chlamydia trachomatis. Therefore, when cefotetan is used in the treatment of pelvic inflammatory disease, and C. trachomatis is one of the suspected pathogens, appropriate antichlamydial coverage should be added. 1.5 Intra-abdominal Infections Cefotetan for Injection and Dextrose Injection is indicated for the treatment of intra-abdominal Infections caused by E. coli , Klebsiella species (including K. pneumoniae ), Streptococcus species, Bacteroides fragilis , Prevotella melaninogenica , Bacteroides vulgatus , and Clostridium species (other than Clostridium difficile [see Warnings and Precautions (5.4 ) ]. 1.6 Bone and Joint Infections Cefotetan for Injection and Dextrose Injection is indicated for the treatment of bone and joint infections caused by Staphylococcus aureus (methicillin susceptible). 1.7 Prophylaxis The preoperative administration of Cefotetan for Injection and Dextrose Injection may reduce the incidence of certain postoperative infections in patients undergoing surgical procedures that are classified as clean, contaminated or potentially contaminated (e.g., cesarean section, abdominal or vaginal hysterectomy, transurethral surgery, biliary tract surgery, and gastrointestinal surgery). If there are signs and symptoms of infection, specimens for culture should be obtained for identification of the causative organism so that appropriate therapeutic measures may be initiated. 1.8 Usage To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefotetan for Injection and Dextrose Injection and other antibacterial drugs, Cefotetan for Injection and Dextrose Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antimicrobial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
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