SITAGLIPTIN AND METFORMIN HYDROCHLORIDE (JANUMET XR) Nursing Considerations

What is the generic name?

SITAGLIPTIN AND METFORMIN HYDROCHLORIDE

What is the Trade Name for SITAGLIPTIN AND METFORMIN HYDROCHLORIDE?

JANUMET XR

What are the Indications for SITAGLIPTIN AND METFORMIN HYDROCHLORIDE?

• 1 INDICATIONS AND USAGE JANUMET ¬Æ XR is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. JANUMET XR is a combination of sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, and metformin hydrochloride (HCl), a biguanide indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. ( 1 ) Limitations of Use: Not for the treatment of type 1 diabetes. ( 1 ) Has not been studied in patients with a history of pancreatitis. ( 1 , 5.2 ) Limitations of Use JANUMET XR should not be used in patients with type 1 diabetes mellitus. JANUMET XR has not been studied in patients with a history of pancreatitis. It is unknown whether patients with a history of pancreatitis are at increased risk for the development of pancreatitis while using JANUMET XR. [See Warnings and Precautions (5.2) .]

References: https://open.fda.gov/