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Alanine Aminotransferase (ALT)

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What is the Lab Name for Alanine Aminotransferase?

Alanine Aminotransferase

What is the Lab Abbreviation for Alanine Aminotransferase?

ALT

What is Alanine Aminotransferase in terms of Nursing Labs?

ALT is an enzyme made in the liver.  This enzyme is found in highest concentrations in the liver , but is found to lesser extent in heart, skeletal muscle and kidney.  Damage to the liver results in a significant increase in this enzyme.

What is the Normal Range for Alanine Aminotransferase?

13 – 69 U/L

What are the Indications for Alanine Aminotransferase?

  • Monitoring
    • progression of liver disease or liver damage
  • It can also aid in monitoring response to treatments

What would cause Increased Levels of Alanine Aminotransferase?

  • Cirrhosis
  • Muscle damage
  • Preeclampsia
  • Biliary tract obstruction
  • Burns
  • Pancreatitis
  • Long-term alcohol abuse
  • Liver Cancer
  • Muscular dystrophy
  • MI
  • Myositis
  • Shock
  • Infections mononucleosis

What would cause Decreased Levels of Alanine Aminotransferase?

  • Pyridoxal phosphate deficiency

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