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Okay. They're also going to complain of pain. So they're going to have lower back pain, leg pain, abdominal pain, or they are going to be in pain. They're also going to be, you're going to notice they're going to be irritable. They are going to, uh, complain of being depressed and they are going to, uh, report significant weight loss. These patients are going to be thin. Um, these patients, when you see them and you're going to observe them. Some of the objective things that you're going to notice is you're going to notice that on their vital signs, they are going to have low BP. They're going to have decreased blood pressure. Their electrolytes are going to be way out. So you may see them with hyponatremia or low sodium, or hyperkalemia. Uh, they're going to have high potassium. They're also going to have severe vomiting and diarrhea.
They're going to be losing those electrolytes that way. They're also going to have some dehydration as well as it's possible that they'll have some, uh, loss of consciousness. So when, uh, caring for these patients, some things that we want to focus on, the first thing that we want to do is we want to get them hooked up to an EKG, and we want to monitor for signs of high potassium or hyperkalemia. And the reason why is because they have low aldosterone levels. And aldosterone is just a hormone that regulates sodium and potassium. It retains potassium and it loses sodium. So if aldosterone is low because of Addison's, that means potassium is high. So low aldosterone equals high K. The next thing we want to do is we want to monitor for signs of dehydration. We want to take a look at their mucus membranes, their skin turgor.
Remember, if a patient is tense, when you assess the skin turgor, that means that they are dehydrated. And this is very common when the patient has severe diarrhea and vomiting. Following that, we want to encourage oral fluids when necessary. And we want to make sure that we monitor their ins and outs, and we want to make sure we let them know that we will need to institute some IV fluids if they are not able to take PO because of the vomiting. The low cortisol levels, uh, create a space where they're not able to drink. Uh, they are not able to maintain their adequate sodium level and, uh, they have decreased urine output. So, their urine output is decreased. Okay. The urine will be concentrated and much darker as well. We want to make sure we administer appropriate medication. So, there's three medications off the top that we want to think of if we want to think about Kayexalate, which is something that's given to reduce potassium levels.
Okay, excellent. And just in K exit K exit. So the K is going out. Cortef or any type of steroid prednisone, that's going to increase cortisol levels. And then, also Florinef. That's also going to, uh, promote replacement and retention of sodium. So we want to make sure we keep that sodium in water. Finally, we want to keep their vitals in the front and an increased temperature can indicate an Addisonian crisis, uh, in the decreased BP can indicate dehydration. Some key points that we want to focus on when taking care of these patients. Uh, first thing, the adrenal glands, when they fail to produce an adequate amount of, uh, hormones, cortisol, aldosterone, and androgens, that's when a patient can develop Addison's disease. Some things that they're going to tell you, pain, think pain, abdominal pain, leg pain, back pain. They're going to be irritable, uh, weight loss. We're going to notice some, uh, low BP, some hypotension, low sodium increased, uh, potassium levels. Also, they're going to have some vomiting and diarrhea. They're going to be dehydrated, Medications that we're going to administer, Kayexalate to lower that K uh, Cortef have to increase that cortisol level and Florinef, enough to increase their sodium levels. We want to do EKG and frequent vitals because the EKG is going to show any arrhythmias because of the hyperkalemia, the increased potassium and a fever may indicate Addisonian crisis.
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